Publications

2017

Fourteen Draft Genome Sequences for the First Reported Cases of Azithromycin-Resistant Neisseria gonorrhoeae in Ireland

Differential carriage of virulence-associated loci in the New Zealand Rangipo outbreak strain of Mycobacterium tuberculosis.

Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response.

The role of acute and chronic respiratory colonization
and infections in the pathogenesis of COPD.

Understanding COPD-overlap syndromes.

Microbiomes in respiratory health and disease:An Asia-Pacific perspective.

 

2016

Typhlocolitis associated with Clostridium difficile ribotypes 078 and 110 in neonatal piglets from a commercial Irish pig herd.

Draft Genome Sequence of a New Zealand Rangipo Strain of Mycobacterium tuberculosis

Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile

Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection

Possible Interplay Between Hospital and Community Transmission of a Novel Clostridium Difficile Sequence Type 295 Recognized by Next-Generation Sequencing.

Characterization of Escherichia coli bloodstream isolates associated with mortality.

Enhanced tracking of the nosocomial transmission of endemic ST22-MRSA-IV among patients and environmental sites using whole-genome sequencing

2015

Whole-genome sequencing improves discrimination of relapse from reinfection and identifies transmission events among patients with recurrent Clostridium difficile infections (2015 in press)

Identification of emergent blaCMY-2-carrying Proteus mirabilis lineages by whole-genome sequencing

Draft genome sequence of a Drug Susceptible New Zealand isolate of Mycobacterium tuberculosis Lineage 3 (2015 in press)

Detailed characterisation of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland, The Journal of Antimicrobial Chemotherapy, (2015 )

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.

2014

Draft genome sequence of a Multi-Drug Resistant (MDR) New Zealand isolate of Mycobacterium tuberculosis Lineage 3 (2014)

Draft genome sequence of the first isolate of Extensively-Drug Resistant (XDR) Mycobacterium tuberculosis in Ireland (2014)

Draft genome sequence of the first isolate of Extensively-Drug Resistant (XDR) Mycobacterium tuberculosis in New Zealand (2014)

2012

The non-classical ArsR-family repressor PyeR (PA4354) modulates biofilm formation in Pseudomonas aeruginosa (2012)

Characterization of imipenem resistance mechanisms in Pseudomonas aeruginosa isolates from Turkey (2012)

MexT functions as a redox-responsive regulator modulating disulphide stress resistance in Pseudomonas aeruginosa (2012)

2011

PhD Thesis – Investigating the Regulatory Mechanisms of Antibiotic Resistance in Gram-negative Pathogens (2011)

2010

Emergence of extended-spectrum beta-lactamase and fluoroquinolone resistance genes among Irish multidrug-resistant isolates (2010)

2009

Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa (2009)

MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump (2009)